Advanced High Throughput Non-Invasive Electrical/TEER Screening of 2D and 3D In Vitro Models
24 and 96 Multiwell Capability Accelerates Life Science Discoveries of Novel Drugs and Therapeutics

EVOM™ Auto, with both 24 and 96 HTS multiwell plate capability, is a high throughput screening (HTS) platform offering fast, noninvasive sample scanning by comparing electrical resistance measurements (transepithelial/transendothelial electrical resistance: TEER). TEER measurement experiments are simple to set up and less time consuming than more complex molecular studies. TEER measurement can be used as the primary scanning method to identify any physiological changes that can then be further evaluated by other methods. EVOM™ Auto can capture TEER measurements in 24 and 96 HTS multiwell plates from Corning, Millipore, or MatTek. The sample preparation time in these HTS plates is efficient, allowing for fast, multi-channel pipetting options.

Additionally, the EVOM™ Auto electrode disinfection capability during measurement minimizes sample cross-contamination. Its wireless device control offers the convenience of operating the instrument from a distance, and the small footprint of EVOM™ Auto enables you to use it inside a sterile cell culture hood or an incubator. The EVOM™ Auto provides a fast and efficient platform for early drug discovery, by narrowing down drug targets and drug concentrations through automated, non-invasive sample scanning.

EVOM™ AUTO EXPEDITES DRUG DEVELOPMENT AND LIFE SCIENCE RESEARCH BY ACCELERATING:

Hit Discovery Process
Hit To Lead
Target Screening, Identification and Validation
Formulation Optimization & Improving Bioavailability
Assay Development
Safety Assessment: Toxicity
Quality Control of 2-D and 3-D
In Vitro Tissue Models in Drug Discovery

APPLICATIONS

	Confluence of Monolayer
	Toxicity
	Blood Brain Barrier (BBB)
	Epithelial and Endothelial Barrier Studies

	Intestinal Drug Absorption: ex. Caco-2, 3-D Tissue Function, Primary Cell
	Lung In Vitro Models for COVID Study, Lung Viral Infection
	Cancer Tissue Studies
	Antibody-Antigen Binding

EVOM™ Auto TEER Measurement System (EVA-MT-03-xx) includes the autosampler, an electrode array with accessories (for 96 or 24 HTS multiwell plates), an interface unit and its cable, an iPad control tablet with software, and a power cord.

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