Solutions For Studies with Zebrafish at Different Life Stages
Oocytes, Embryo, Larvae and Adults

lifecycle

WPI has been serving scientists for over 50 years with easy and cost-effective tools for genetic modification. WPI offers a wide range of instruments required for microinjection of zebrafish in oocytes, embryo, larvae, and adults to enable genetic modification.

Research Areas

	Developmental Biology
	Oncology
	Toxicology
	Genetics
	Regenerative Medicine

Pharmacology

Direct Cardiovascular Measurements

Embryonic Zebrafish have become a popular model for cardiovascular research. WPI is a pioneer in developing instruments for research in electrophysiology and is cited in 1000s of peer-reviewed publications. WPI introduced the CardioPhys™ Z series of products that makes measurement of cardiovascular functionalities in zebrafish embryo easy.

Detection of Free Radicals & Other Molecules for Disease Models

The WPI Free Radical Analyzer, TBR4100, enables real-time, highly sensitive NO, H₂O₂, H₂S, CO, O₂-important physiological indicators in intracellular cell signaling and homeostasis. Free radicals beyond the level of normal detoxification can result in oxidative stress (OS). OS affects wound healing and aging, and it causes several diseases such as diabetes mellitus, neurodegenerative disorders (Parkinson's Disease, Alzheimer's disease and Multiple Sclerosis), cardiovascular diseases (atherosclerosis and hypertension), respiratory diseases (asthma), cataract development, rheumatoid arthritis and various cancers (colorectal, prostate, breast, lung, bladder cancers).

Accessories

MICROINJECTION SETUP

ecg setup

The WPI M3301 Micromanipulators, Electrode Holders, Pre-Pulled Glass Micropipettes and Z-MOLDS were used in this application. The CardioPhys™ ECG is not shown.

Z-MOLDS FOR CUSTOM AGAROSE GEL TEMPLATES

Z-Molds

Z-MOLDS Microinjection & Transplantation Molds (4 per kit) are turned upside down and placed in liquid agarose gel. Pipette the embryos into the grooves. The embryos self-align.